Description
25I-NBOMe (also known as 2C-I-NBOMe or “25I”) is a potent synthetic psychedelic substance derived from the phenethylamine class. It acts as a selective agonist for the 5-HT2A serotonin receptor, which is responsible for its hallucinogenic effects. Here are some key points about 25I-NBOMe:
Key Characteristics:
- Chemical Name: 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine
- Class: NBOMe series (substituted phenethylamine)
- Dosage: Active in microgram (µg) ranges (typically 50–1000 µg, but doses above 500 µg can be dangerous)
- Duration: Effects last 6–10 hours, depending on dose and route of administration.
Effects:
- Positive Effects:
- Visual and auditory hallucinations
- Enhanced sensory perception
- Euphoria and altered thought patterns
- Increased emotional intensity
- Negative Effects:
- Severe vasoconstriction (dangerous blood vessel tightening)
- Hypertension (high blood pressure)
- Seizures
- Paranoia, anxiety, or panic attacks
- Risk of serotonin syndrome (especially when mixed with other drugs)
- Potential for overdose (even at relatively low doses)
Risks & Dangers:
- High potency makes accurate dosing difficult, increasing overdose risk.
- Toxicity: Linked to multiple fatalities, often due to cardiovascular complications or seizures.
- Misrepresentation: Often sold as LSD (on blotter paper), but unlike LSD, it has a bitter/metallic taste.
- Legal Status: Classified as a Schedule I controlled substance in many countries (USA, UK, etc.), meaning it has no accepted medical use and a high potential for abuse.
Harm Reduction Tips:
- Test your substance (using reagent tests like Ehrlich’s or Marquis to distinguish from LSD).
- Start with a very low dose (if used at all) due to unpredictable effects.
- Avoid mixing with other stimulants or serotonergic drugs (e.g., MDMA, SSRIs).
- Have a sober trip sitter present if experimenting.
Legality:
- United States: Schedule I under the Federal Analog Act.
- United Kingdom: Class A under the Misuse of Drugs Act.
- Australia: Schedule 9 (prohibited substance).
- Canada: Controlled under the Controlled Drugs and Substances Act.
Conclusion:
25I-NBOMe is not considered safe for recreational use due to its high risk profile. Many harm reduction organizations strongly advise against its use because of the potential for severe adverse effects, including death. If you or someone you know is considering using it, extreme caution and thorough research are essential.
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