Description
What is Xtampza ER?
Xtampza ER is a brand name for oxycodone extend-release. It is prescribe for individuals suffering from moderate to severe pain, especially for long-term conditions, such as chronic back pain, cancer pain, or pain resulting from injury or surgery. As an extend-release (ER) formulation, Xtampza ER is design to provide consistent pain control, reducing the need for frequent dosing throughout the day.
Side Effects
Like all opioids, Xtampza ER can cause side effects, some of which can be severe. Common side effects include:
- Constipation
- Drowsiness or sedation
- Nausea and vomiting
- Dizziness
- Headache
More serious side effects can include:
- Respiratory depression (slowed or shallow breathing), which is a serious risk with all opioids, especially in higher doses or when combined with other central nervous system (CNS) depressants.
- Addiction, abuse, and misuse: Xtampza ER has the potential for abuse and addiction, and it should be used only by individuals for whom it is prescribed. Misuse of oxycodone can lead to overdose and death.
- Severe allergic reactions: Symptoms may include rash, swelling, or trouble breathing.
- Liver and kidney issues: Patients with liver or kidney impairment should use Xtampza ER with caution, as it may require dose adjustments.
- Withdrawal symptoms: If stopped abruptly, Xtampza ER can cause withdrawal symptoms, including agitation, nausea, muscle pain, and anxiety.
Precautions and Warnings
- Addiction, Abuse, and Misuse: this contains oxycodone, an opioid with a high potential for abuse, addiction, and overdose. It should only be prescribed for patients who require long-term pain relief and when other pain treatments are ineffective.
- Respiratory depression: As with other opioids, Xtampza ER can slow or stop breathing, especially in higher doses or when combined with other sedating medications such as benzodiazepines, alcohol, or other opioids.
- Risk of overdose: Taking more than the prescribed dose of Xtampza ER can result in overdose, potentially leading to death. Symptoms of overdose include severe drowsiness, slow breathing, and loss of consciousness.
- Pregnancy and breastfeeding:It is classified as a pregnancy category C medication, meaning it may harm a fetus. It is not recommended during pregnancy unless the potential benefits outweigh the risks. It can also pass into breast milk and harm a nursing infant, so it should be avoided during breastfeeding.
- Elderly patients: Older adults may be more susceptible to the side effects of this, including sedation, confusion, and respiratory depression.
Drug Interactions
This can interact with other medications, including:
- CNS depressants (e.g., alcohol, benzodiazepines, other sedatives): Combining this with these medications can increase the risk of respiratory depression, sedation, and overdose.
- Antidepressants (SSRIs, SNRIs): There is a risk of serotonin syndrome when opioids are combined with certain antidepressants.
- Other opioids: Using multiple opioids simultaneously increases the risk of overdose.
- Anticoagulants (e.g., warfarin): This may increase the risk of bleeding when combined with blood thinners.
Overdose and Emergency Treatment
An overdose of this is a medical emergency. Symptoms of overdose include:
- Severe drowsiness
- Slow or shallow breathing
- Loss of consciousness
- Pinpoint pupils
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