Description

Ketorolac: An Overview

What is Ketorolac? Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) commonly use for its powerful analgesic properties. It is often prescribe for short-term management of moderate to severe pain, particularly following surgeries or for conditions like kidney stones.

Mechanism of Action Ketorolac works by inhibiting the production of prostaglandins, substances in the body that mediate inflammation and pain. By blocking the enzyme cyclooxygenase (COX), ketorolac reduces pain and inflammation effectively.

Forms and Dosage Ketorolac is available in various forms, including:

• Oral tablets
• Injectable solutions
• Eye drops (for treating ocular pain)

Typically, the injectable form is used in a clinical setting, while oral tablets may be prescribed for home use. The usual duration of treatment should not exceed 5 days due to potential side effects, particularly gastrointestinal issues and renal impairment.

Indications This is indicated for:

• Post-operative pain relief
• Acute pain management
• Pain associated with inflammatory conditions

Side Effects Common side effects may include:

• Gastrointestinal discomfort (nausea, vomiting, diarrhea)
• Headaches
• Dizziness
• Increased risk of bleeding

Serious side effects can occur, including:

• Gastrointestinal ulcers or bleeding
• Kidney dysfunction
• Allergic reactions

Contraindications This should be avoided in patients with:

• Peptic ulcer disease
• Severe renal impairment
• History of allergic reactions to NSAIDs
• Concurrent use of anticoagulants

Conclusion Ketorolac is a potent NSAID effective for short-term pain management. However, due to its potential side effects, it is essential to use it under medical supervision, particularly for individuals with existing health conditions or those taking other medications. Always consult a healthcare professional before starting or stopping any medication.